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FLASH GENE
Symbol ISLR2 contributors: mct - updated : 15-06-2021
HGNC name immunoglobulin superfamily containing leucine-rich repeat 2
HGNC id 29286
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • immunoglobulin domain
  • leucine-rich repeat
  • HOMOLOGY
    Homologene
    FAMILY
  • leucine-rich repeat and immunoglobulin family of membrane proteins
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involvement of ISLR2 in axon guidance and cell-cell communication
  • potential role role for iSLR2 in the regulation of complex forebrain connectivity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) HAAD
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
  • Linx-deficient mice develop severe hydrocephalus and die perinatally