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FLASH GENE
Symbol ISY1 contributors: mct - updated : 20-02-2013
HGNC name ISY1 splicing factor homolog (S. cerevisiae)
HGNC id 29201
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • ISY1 family
  • CATEGORY DNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • implicated in the first catalytic step of splicing and splicing fidelity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with the ATPase DHX38 to regulate the fidelity of pre-mRNA splicing
  • multiple functions for SRRM2 in the splicing process, including an important role in the activation of splicing in association with ISY1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS