Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | MAN1B1 | contributors: shn - updated : 08-01-2014 |
HGNC name | mannosidase, alpha, class 1B, member 1 |
HGNC id | 6823 |
|
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| |
|
HOMOLOGY |
interspecies | ortholog to Man1B1, Rattus norvegicus |
ortholog to Man1B1, Mus musculus | |
ortholog to man1b1, Danio rerio | |
ortholog to MAN1B1, Pan troglodytes |
Homologene |
FAMILY | glycosyl hydrolase 47 family |
CATEGORY | enzyme |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
text | N-glycan biosynthesis c |
PATHWAY |
metabolism | carbohydrate |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule | cofactor, |
calcium |
protein |
cell & other |
REGULATION |
inhibited by | the class I alpha-mannosidase inhibitors 1-deoxymannojirimycin and kifunensine |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
HOMOLOGY |
interspecies | ortholog to Man1B1, Rattus norvegicus |
ortholog to Man1B1, Mus musculus | |
ortholog to man1b1, Danio rerio | |
ortholog to MAN1B1, Pan troglodytes |
Homologene |
FAMILY |
CATEGORY |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
inhibited by | the class I alpha-mannosidase inhibitors 1-deoxymannojirimycin and kifunensine |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
HOMOLOGY |
interspecies | ortholog to Man1B1, Rattus norvegicus |
ortholog to Man1B1, Mus musculus | |
ortholog to man1b1, Danio rerio | |
ortholog to MAN1B1, Pan troglodytes |
Homologene |
FAMILY |
CATEGORY |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
inhibited by | the class I alpha-mannosidase inhibitors 1-deoxymannojirimycin and kifunensine |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
HOMOLOGY |
interspecies | ortholog to Man1B1, Rattus norvegicus |
ortholog to Man1B1, Mus musculus | |
ortholog to man1b1, Danio rerio | |
ortholog to MAN1B1, Pan troglodytes |
Homologene |
FAMILY |
CATEGORY |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
inhibited by | the class I alpha-mannosidase inhibitors 1-deoxymannojirimycin and kifunensine |
ASSOCIATED DISORDERS |
corresponding disease(s) | MRT15 , CDG2T |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |