basic FUNCTION
| may be involved in transcriptional regulation |
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able to repress transcription in a methyl-dependent manner, yet their tissue-specific expression pattern suggests nonoverlapping functions |
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represses transcription of CDKN1A and controls the cellular response to TP53 activation |
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epigenetic regulator with high affinity for methylated CpGs that localizes at pericentromeric heterochromatin and is frequently downregulated in cancer |
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is a transcriptional repressor that regulates the cell cycle, including the apoptotic response to amyloid beta |
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is an essential component in maintaining genomic stability in mammals |
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ZBTB4 exhibited a tumor suppressive role in Ewing sarcoma (ES) possibly by reducing Survivin expression |