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FLASH GENE
Symbol SSH2 contributors: - updated : 16-12-2004
HGNC name slingshot 2
HGNC id 30580
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a phosphatase domain distantly related to those of the family of mitogen-activated protein kinase phosphatases
HOMOLOGY
Homologene
FAMILY SSH gene family
CATEGORY motor/contractile
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria
intracellular,nucleus
basic FUNCTION
  • regulating mitogenic signal transduction by dephosphorylating both THR and TYR residues on map kinases ERK1 and ERK2
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS