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FLASH GENE
Symbol ARHGAP20 contributors: - updated : 28-09-2005
HGNC name Rho GTPase activating protein 20
HGNC id 18357
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a RA (RasGTP-binding) domain (codon 198-274)
  • a RhoGAP domain (codon 363-546)
  • and two Annexin-like (ANXL) repeats (codon 657-767 and 796-909)
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory , tumor suppressor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • may be involved in rearrangements of the cytoskeleton and cell signaling events that occur during spermatogenesis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   deletion   loss of function
    in breast cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS