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FLASH GENE
Symbol SLC15A2 contributors: mct - updated : 24-05-2008
HGNC name solute carrier family 15 (H+/peptide transporter), member 2
HGNC id 10921
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • twelve TM domains
  • a long hydrophilic segment between TM domain 9 and 10
  • HOMOLOGY
    Homologene
    FAMILY PTR2/POT transporter family
    CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • mediating the cellular uptake of di- and tripeptides as well as a variety of drug molecules
  • mediates the high-affinity low-capacity transport of small peptides as well as various oral peptide-like drugs in the kidney
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacting with PDZK1 (plays a physiologically important role in both oligopeptide handling as well as peptide-like drug transport in the kidney)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS