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FLASH GENE
Symbol ENPP6 contributors: - updated : 02-03-2007
HGNC name ectonucleotide pyrophosphatase/phosphodiesterase 6
HGNC id 23409
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
an NPP domain with significant homology to NPP4, NPP5, and NPP7/alkaline sphingomyelinase
HOMOLOGY
interspecies homolog to murine Enpp6
Homologene
FAMILY ENPP family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • choline-specific glycerophosphodiester phosphodiesterase
  • hydrolyzes LPC to form monoacylglycerol and phosphorylcholin
  • having a specific role through the hydrolysis of polyunsaturated lysophosphatidylcholine, glycerophosphorylcholine, or sphingosylphosphorylcholine in kidney and brain
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    nucleotide metabolism
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS