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Symbol OPN5 contributors: mct - updated : 12-06-2012
HGNC name opsin 5
HGNC id 19992
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
seven transmembrane receptor
HOMOLOGY
interspecies homolog to murine Opn5
Homologene
FAMILY
  • rhodopsin family
  • g-protein coupled receptors
  • opsin subfamily
  • CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION     plasma membrane
    text integral membrane protein
    basic FUNCTION
  • rhodopsin-like receptor activity
  • first and hitherto unknown human opsin with peak sensitivity in the UV region
  • potentially triggers a UV-sensitive Gi-mediated signaling pathway in the mammalian tissues
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • capable of activating heterotrimeric G protein Gi in a UV-dependent manner
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS