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FLASH GENE
Symbol SEMA6D contributors: mct - updated : 25/10/2008
HGNC name sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
HGNC id 16770
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a semaphorin (SEMA) domain and a PSI domain
HOMOLOGY
Homologene
FAMILY semaphorin family
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • may be playing a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation
  • playing a role as a regulator of the late phase of primary immune responses
  • regulates T cell activation during the late phases of an immune response
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS