basic FUNCTION
| suppresses neurite outgrowth |
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promotes innervation and survival of inner ear sensory neurons by regulating the expression of trophic and/or tropic factors including neurotrophins from sensory epithelia |
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has a critical role in the development of the inner ear neural circuit |
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implicated in mediating basic neuronal processes, ranging from neurite outgrowth and dendritic elaboration to neuronal survival |
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SLITRK1, SLITRK2, SLITK3, SLITRK4, SLITRK5 and SLITRK6 are differentially localized to distinct synapse types and regulate the formation of the respective synapses in an isoform-dependent manner |