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FLASH GENE
Symbol RAB43 contributors: mct - updated : 27-04-2012
HGNC name RAB43, member RAS oncogene family
HGNC id 19983
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY isy1-like splicing family
CATEGORY signaling , transport
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm
intracellular,nucleus
basic FUNCTION
  • involved in intracellular transport
  • RAB1A and RAB43 are key Rabs required for the biogenesis and maintenance of a functional Golgi structure, and suggest that other Rabs acting at the Golgi complex are likely to be functionally redundant
  • RAB18 and RAB43, strongly indicated roles in ER-Golgi trafficking
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • redistributes the p150(Glued) subunit of DCTN1, consistent with a specific role in regulating association of pre-Golgi intermediates with microtubules
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS