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FLASH GENE
Symbol TSEN2 contributors: mct/npt - updated : 26-03-2007
HGNC name tRNA splicing endonuclease 2 homolog (S. cerevisiae)
HGNC id 28422
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • catalytic C-terminal domain
  • HOMOLOGY
    interspecies homolog to murine Tsen2
    Homologene
    FAMILY
  • tRNA-intron endonuclease family
  • CATEGORY enzyme , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • requiring for cell growth and division, catalyzing the removal of introns, the first step in tRNA splicing
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) PCH2B
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS