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FLASH GENE
Symbol MED24 contributors: mct - updated : 18-10-2016
HGNC name mediator complex subunit 24
HGNC id 22963
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a P-loop predicted to be an ATP/GTP-binding site
HOMOLOGY
Homologene
FAMILY
CATEGORY receptor nuclear
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • playing a role in nuclear hormone receptor-mediated transactivation
  • coactivator required for transcriptional activation of RNA polymerase II transcribed genes by DNA binding transcription factors
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • regulates the proper splicing of transcripts encoding for pluripotency regulators such as POU5F1, PRDM14, E4F1 and MED24
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS