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Symbol NUDT16L1 contributors: mct - updated : 16-05-2017
HGNC name nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
HGNC id 28154
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a Nudix (Nudt) motif
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY adhesion , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • is inactive for RNA decapping but retains RNA-binding activity
  • potential molecular function of NUDT16L1 in the regulation of cell signaling via binding to SDC4
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • with paxillin (PXN ) and SDC4, syndecan 4(for the cooperative signaling in the assembly of focal adhesion and actin stress fibers)
  • co-localized with SDC4 cytoplasmic domain in focal contacts, interacts with various cell adhesion adaptor proteins to control cell signaling
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS