basic FUNCTION
| potential guanine nucleotide exchange factor |
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DOCK1 and DOCK5 are critical regulators of the fusion step during primary myogenesis |
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potential role of DOCK5 in human obesity |
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DOCK1 and DOCK5 are not the important exchange factors regulating RAC1 activity during the establishment and maintenance of the glomerular barrier |
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atypical guanine nucleotide exchange factor (GEF) for RAC1, that is essential for mast cell degranulation |
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is a key signaling adaptor that orchestrates remodeling of the microtubule network essential for mast cell degranulation |
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DOCK5 acts with DOCK2 in neutrophils to regulate multiple cellular functions |
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DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation |
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expression of TNS3 and DOCK5 concomitantly increase during osteoclast differentiation |
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DOCK5 and TNS3 cooperate for osteoclast activity, to ensure the correct organization of podosomes |
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is a key regulator of epithelial invasion and metastasis |