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FLASH GENE
Symbol CNTN3 contributors: npt/ - updated : 06-10-2006
HGNC name contactin 3 (plasmacytoma associated)
HGNC id 2173
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • six Ig-like and four FNIII-like extracellular domains,
  • a single transmembrane segment (1TM)
  • a short cytoplasmic tail
  • HOMOLOGY
    interspecies homolog to murine Pang
    Homologene
    FAMILY
  • immunoglobulin superfamily
  • contactin family
  • CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • neural recognition molecule, mediating cell surface interactions during nervous system development
  • having some neurite outgrowth-promoting activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with PTPRG (Abdelhakim 2010)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to autism spectrum disorder
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS