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FLASH GENE
Symbol TOMM7 contributors: mct/npt - updated : 14-06-2008
HGNC name translocase of outer mitochondrial membrane 7 homolog (yeast)
HGNC id 21648
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • DNAPK phosphorylation site
  • two N-myristoylation motifs
  • mono polymer complex
    HOMOLOGY
    Homologene
    FAMILY
  • Tom7 family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,outer
    intracellular,cytoplasm,organelle,membrane
    basic FUNCTION
  • involved in intracellular protein transport
  • may play a role in destabilizing the interactions between the TOM complex and the TOM receptor
  • required for stabilization of the TOM complex
  • CELLULAR PROCESS protein, post translation, targeting
    PHYSIOLOGICAL PROCESS cellular trafficking transport , mitochondrial transport
    PATHWAY
    metabolism
    signaling
    a component
  • small regulatory component of the translocase of the outer mitochondrial membrane
  • C9orf105 as well as TOMM7, were associated with TOMM40 in the TOM complex
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • complexed with TOM40 and TOM22
  • cell & other
    REGULATION
    Other levels of TOM22 in mitochondria can accelerate the rate of TOMM7 assembly into the mature TOM complex
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS