basic FUNCTION
| self-associates and interacts with capping protein with affinities that, given the cellular concentrations of the proteins |
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key regulator of CP (capping protein) and has profound effects on cell behavior |
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may play an important role in the physiological regulation of actin assembly |
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LRCC16A and LRRC16B were necessary for cell migration, but for different reasons ( |
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inhibits the actin capping action of heterodimeric capping protein |
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promotes uncapping by binding to a freely accessible site on capping protein (CP) bound to a filament barbed end and inducing a change in the conformation of the actin-binding surface of CP |
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cytoskeletal scaffold that has crucial roles in cell motility and tissue development through interactions with cytoskeletal effectors and regulation of capping protein at the leading edge |
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role of LRRC16A in platelet formation |