Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TBC1D7 | contributors: npt/mct - updated : 09-04-2014 |
HGNC name | TBC1 domain family, member 7 |
HGNC id | 21066 |
|
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
HOMOLOGY |
interspecies | homolog to murine 2610009C09Rik |
homolog to rattus LOC361227 |
Homologene |
FAMILY |
CATEGORY | regulatory |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytosolic,vesicle |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component | TSC1-TSC2-TBC1D7 complex , TSC1-TSC2-TBC1D7 (TSC-TBC) complex is the functional complex that senses specific cellular growth conditions and possesses Rheb-GAP activity |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
|
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | MGCPH |
Other morbid association(s) |
|
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
| Selective suppression of TBC1D7 and/or inhibition of the TBC1D7-TSC1 complex formation could be promising therapeutic strategies for lung cancer therapy (Sato 2010) |
| |
ANIMAL & CELL MODELS |