basic FUNCTION
| proapototic factor that links PAWR to promyelocytic leukemia (PML) nuclear bodies |
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potentiates both serum withdrawal- and TNF alpha-induced apoptosis |
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functioning as zinc-dependent sequence-specific DNA-binding factors with roles in proliferation, apoptosis, cell cycle, chromosome segregation, chromatin modification, and transcriptional regulation |
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having an important function in cell proliferation and cell cycle control |
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endogenous physiological regulator of endothelial cell proliferation and G1/S cell cycle progression |
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with others THAP proteins could play a major role in targeting genes to promote transcription regulation through interactions with protein complexes associated to chromatin remodelling |
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transcription factor that represses the expression of DYT1 |
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plays a critical role in G(1)-S cell cycle control |
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may function as part of a cell surface-nucleus signaling cascade involved in terminal neural differentiation |