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FLASH GENE
Symbol KCNG4 contributors: - updated : 13-04-2004
HGNC name potassium voltage-gated channel, subfamily G, member 4
HGNC id 19697
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
K+ channel tetramerisation domain
mono polymer heteromer , tetramer
HOMOLOGY
Homologene
FAMILY K+ channel family, G subfamily
CATEGORY regulatory , transport channel
SUBCELLULAR LOCALIZATION     plasma membrane
text remains intracellular in the absence of KCNB1
basic FUNCTION
  • modulates channel activity by shifting the treshold and the half-maximal activation to more negative values
  • controls the excitability of electrically active cells
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein heteromultimerizing with KCNB1, KCNC1 and KCNF1 to form the K+ channel
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS