protein
| interacting with STIP1, PARK2, GPR37, HSPA8, CCT1, CCT2, CCT3, CCT4, CCT5, CCT6A, CCT7, CCT8 |
|
binding to microtubules and alpha/beta-tubulin heterodimers with high affinity |
|
MEIG1/PACRG forms a complex in the manchette and this complex is necessary to transport cargos, such as SPAG16, to build the sperm flagella |
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EFHC1 (EF-hand containing 1), a potential PACRG interaction partner similarly associated with the protofilament ribbon and ciliary motility, also positively regulates lifespan |
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PACRG and FAP20 comprise the inner junction bridge that serves as a hub for both directly modulating dynein-driven microtubule sliding, as well as for the assembly of additional ciliary components that play essential roles in generating coordinated ciliary beating |
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PACRG binds to the adaptor protein meiosis expressed gene 1 (MEIG1) |
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similarly to PRKN, PACRG promoted NFKB1 activation in response to TNF |