basic FUNCTION
| mediating the entry of calcium ions into excitable cells |
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also involved in a variety of calcium-dependent processes, including muscle contraction, neurotransmitter release, gene expression, cell motility, cell division and cell death |
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nonselective cation channel, forming the background Na(+) leak conductance and controling neuronal excitability |
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has been shown to be responsible for the TTX-resistant sodium leak current implicated in the regulation of neuronal excitability |
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extracellular Ca(2+) influences neuronal excitability through the UNC79-UNC80-NALCN complex in a G protein-dependent fashion |
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is essential for the depolarization of clock neurons in the morning and the maintenance of normal circadian rhythms |
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role in conducting the background Na(+) current that depolarizes resting membrane properties of pacemaker neurons |
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can serves as a variable sensor that responds to calcium or sodium ion flux, depending on whether the total cellular current density is generated more from calcium-selective or sodium-selective channels |
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forms a voltage-independent ion channel with a role in the regulation of neuronal excitability |