Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CD207 | contributors: npt/shn - updated : 18-02-2012 |
HGNC name | CD207 molecule, langerin |
HGNC id | 17935 |
|
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
HOMOLOGY |
interspecies | ortholog to Cd207, Mus musculus |
ortholog to CD207, Pan troglodytes | |
ortholog to Cd207, Rattus norvegicus |
Homologene |
FAMILY | Ca2+ dependant (C-type) lectin family |
CATEGORY | antigen |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle | |
text | localized in the Birbeck granules |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
Other | down-regulated during Langerhans cells maturation |
up-regulated by TGF-beta |
ASSOCIATED DISORDERS |
corresponding disease(s) | BBGRD |
Susceptibility | to infection |
Variant & Polymorphism other | certain haplotypes may differ in their binding to pathogens and thus might be associated with susceptibility to infection |
Candidate gene
Marker
| Therapy target
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| |
ANIMAL & CELL MODELS |