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FLASH GENE
Symbol XPO5 contributors: - updated : 11-03-2006
HGNC name exportin 5
HGNC id 17675
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Xpo5
homolog to rattus LOC363194
Homologene
FAMILY karyopherin family
CATEGORY transport carrier
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm
basic FUNCTION
  • mediates transport of protein between the nuclear and cytoplasmic compartments
  • plays a role in the export of JAZ and ILF3 from the nucleus
  • exports eEF1A via tRNA
  • regulates the translocation of double-stranded RNA-binding domain (dsRBD) proteins to the cytoplasm
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binds NUP214, NUP153
  • interacts with RAN-GTP
  • interacting with STAU2
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS