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FLASH GENE

Symbol

PLA1A

contributors: mct - updated : 13-06-2007

HGNC name	phospholipase A1 member A
HGNC id	17661

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies

homolog to murine Pla1a

Homologene

FAMILY

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	extracellular
text	extracellular PLA1s include phosphatidylserine (PS)-specific PLA1 (PS-PLA1)(Aoki 2007)

basic FUNCTION	involved in phosphatidylserine metabolism
	acting specifically on phosphatidylserine (ps) and lyso-ps to hydrolyze fatty acids at the sn-1 position of these phospholipids
	having a role in the production of lysophospholipid mediators

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

lipid/lipoprotein

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS