basic FUNCTION
| lymphoid nuclear transcriptional activator with DNA-binding capacity and transcription transactivation potential |
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able to bind RNA, having a high apparent affinity for the G-quadruplex structure |
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possible functional redundancy among the AFF family members in the regulation of splicing and transcription |
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functional redundancy for AFF2/AFF3/AFF4 proteins during brain development |
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is one of the targets of the WNT/CTNNB1 pathway, an important contributor to pathways involved in bone development and homeostasis |
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is enriched at gamete differentially methylated regions (DMRs) of the imprinted loci and regulates the imprinted gene expression |