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FLASH GENE
Symbol USP6NL contributors: - updated : 20-09-2004
HGNC name USP6 N-terminal like
HGNC id 16858
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Usp6nl
homolog to rattus LOC291309
Homologene
FAMILY
CATEGORY unknown/unspecified
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • Rab5-specific GTPase activating activity
  • inhibits internalization of EGFR when complexed with EPS8
  • critical for macropinocytosis
  • CELLULAR PROCESS cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with EPS8
  • interacts with F-actin and actinin-4
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS