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FLASH GENE
Symbol FSD1 contributors: - updated : 24-03-2004
HGNC name fibronectin type 3 and SPRY (spla, ryanodine) domain containing (with coiled-coil motif) 1
HGNC id 13745
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a coiled-coil region
  • a fibronectin type III domain
  • a SPRY domain
  • conjugated GlycoP
    mono polymer homomer , dimer , trimer
    HOMOLOGY
    interspecies ortholog to murine Fsd1
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule,centrosome
    text FSD1 dissociates from centrosomes at the G2/M transition nad is recruited back to spindle poles during anaphase (cell-cycle dependent association)
    basic FUNCTION microtubule-binding activity
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    inhibited by phosphorylation by cdk5/p35
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS