basic FUNCTION
| having ATP binding activity |
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suppress H2O2-induced apoptosis by suppression of p38 MAPK signaling, one of the essential pathways for apoptosis |
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thought to be a more relevant tumor-associated antigen in malignant melanoma than is HSPA5 (Park 2009) |
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may play an important role in the refolding of denatured proteins and protection against stress-induced cell death in mammalian cells |
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important element of the Hsp70 chaperone machinery for refolding of denatured proteins and protection against stress-induced cell death in mammalian cells |
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has a primary role promoting CFTR quality control at an earlier stage |