basic FUNCTION
| mediate the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells |
|
functioning as a vesicular glutamate transporter |
|
specifically involved in a functional facet of cholinergic interneurons, acetylcholine release |
|
responsible for vesicular glutamate storage and exocytotic glutamate release in neurons and astrocytes |
|
both SLC17A8 and the cytosolic concentration of glutamate are key limiting factors in regulating the Ca2+-dependent release of glutamate from astrocytes |