basic FUNCTION
| may play a role in dictating the degree of inflammatory response to the respiratory syncytial virus (Allen 2007) |
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demonstrates the properties of a Ras effector and tumor suppressor but exhibits biological properties that are unique and distinct from those of other family members (Allen 2007) |
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implicated in apoptosis in HeLa cells and it triggers both caspase-dependent and caspase-independent pathways (Ikeda 2007) |
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may function as tumour suppressors by regulating the cell cycle and apoptosis (van der Weyden 2007) |
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caused apoptosis when released from activated STK3 in a manner dependent on WW45, the mammalian Salvador homolog (Ikeda 2009) |
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antagonizes Hippo signaling and mediates apoptosis through a pathway that is parallel to the canonical Hippo pathway (Ikeda 2009) |
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stabilizes TP53, regulates apoptosis and the cell cycle, and functions as a tumor suppressor |
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involved in TP53-mediated G1/S arrest |
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RASSF6 may play a tumor suppressor role in the progression of clear cell renal cell carcinoma |