basic FUNCTION
| playing a role in the regulation of cell development, activation, growth and motility |
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functioning as a negative regulator in the adhesion-dependent activation of Ras |
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key component of the glomerular filtration barrier |
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appears to be involved in the establishment, maturation, and/or maintenance of the glomerular basement membrane structure in addition to its role in integrin-mediated adhesion strengthening |
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promotes the formation of epithelial cell-cell contacts in a protein kinase C (PKC) and Cdc42-dependent manner |
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having clearly an important role for HGF-dependent cellular morphogenesis |
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also an important regulator of the stability of tumor cell-cell interactions, potentially through its interaction with alpha3beta1 integrin |
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new role of CD151 in tumorigenesis, whereby it functions as an important regulator of communication between tumor cells and endothelial cells |
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implicated in the regulation of cell-substrate adhesion and cell migration through physical and functional interactions with integrin receptors |
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controls Met-dependent neoplastic growth by enhancing receptor signaling through beta4 integrin-mediated pathways, independent of cell-substrate adhesion |
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'adaptor' between integrins and signal pathways |
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may plays a specific role in promoting prostate cancer cell motility |
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role in maintenance of the specification state in the trigeminal placode, uncovering the first known role for a tetraspanin in a developmental system |
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implicated in cancer progression and metastasis |