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FLASH GENE
Symbol ART4 contributors: - updated : 10-11-2006
HGNC name ADP-ribosyltransferase 4 (Dombrock blood group)
HGNC id 726
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
interspecies ortholog to murine Art4
ortholog to chimpanzee art4
Homologene
FAMILY Arg-specific ADP-ribosyltransferase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     plasma membrane
text attached to the membrane by a GPI-anchor
basic FUNCTION
  • acting as blood group antigen
  • involved in the transfer of the ADP-ribose moiety from NAD+ to a specific amino acid in the target protein
  • CELLULAR PROCESS protein, post translation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor, nucleotide,
    NAD+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) DO
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS