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FLASH GENE
Symbol MALSU1 contributors: mct - updated : 15-06-2015
HGNC name mitochondrial assembly of ribosomal large subunit 1
HGNC id 21721
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY family of DUF143 proteins
CATEGORY RNA associated
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,matrix
basic FUNCTION
  • is potentially a human assembly and/or stability factor involved in the biogenesis of the large subunit of the mitochondrial ribosome
  • is involved in ribosomal large subunit function
  • contributes critically to mitochondrial translation and specifically associates with the large subunit of the mitochondrial ribosome (mt-LSU)
  • contributes critically to mitochondrial translation and specifically associates with the large subunit of the mitochondrial ribosome (mt-LSU), essential for mitochondrial ribosome biogenesis and mitochondrial translation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • associates with the mitochondrial large ribosomal subunit (mt-LSU)
  • mitochondrial ribosomal protein MRPL14 is the specific interacting protein partner of MALSU1 in the mt-LSU
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS