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FLASH GENE
Symbol DYNLRB1 contributors: - updated : 21-02-2006
HGNC name dynein, light chain, roadblock-type 1
HGNC id 15468
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Dncl2a
intraspecies paralog to DNCL2B
Homologene
FAMILY
  • GAMAD family
  • MPP6 family
  • CATEGORY motor/contractile , protooncogene
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule
    basic FUNCTION
  • involved in tumor progression
  • involved in microtubule-based movement
  • involved in assembly and motor function of dynein
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component included in cytoplasmic dynein complex(dynein light chain)
    INTERACTION
    DNA
    RNA
    small molecule
    protein binding with BMF and BCL2L11
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in hepatocellular carcinomas (variant 1)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS