protein
| JAK kinases |
|
activated cytokine receptors |
|
elonguin B/C complex |
|
CKB interacts with ASB9 in a specific, SOCS box-independent manner |
|
ASB9 interacts with the creatine kinase system and negatively regulates cell growth |
|
ankyrin repeat domains of ASB9 can associate with the substrate binding site of CMKT1A in a SOCS box-independent manner |
|
specific substrate-recognition subunit of an elongin C-cullin-SOCS box E3 ubiquitin ligase complex |
|
ASB9 binds to creatine kinase (CKB) and targets it for degradation |