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FLASH GENE
Symbol RGL4 contributors: npt - updated : 23-01-2006
HGNC name ral guanine nucleotide dissociation stimulator-like 4
HGNC id 31911
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one Ras-GEF domain
    • HOMOLOGY
    interspecies ortholog to rabbit rgr
    homolog to chimpanzee LOC458697
    Homologene
    FAMILY
    CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,vesicle
    basic FUNCTION
  • acting as a guanyl-nucleotide exchange factor
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text small GTPase mediated signal transduction
    PATHWAY
    metabolism
    signaling signal transduction
    intracellular signaling cascade
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral somatic mutation      
    or abnormally truncated transcript are involved in malignancies
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS