Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol HCFC1R1 contributors: npt/ - updated : 10-11-2007
HGNC name host cell factor C1 regulator 1 (XPO1 dependant)
HGNC id 21198
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a functional HCF-binding motif
  • a leucine-rich nuclear export sequence
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory , transport carrier
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • shuttling between the nucleus and cytoplasm in a CRM1-dependent manner
  • leading to accumulation of HCF-1 in the cytoplasm when overexpressed
  • regulating HCF-1 activity by modulating its subcellular localization
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding to HCF-1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS