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FLASH GENE
Symbol TMEM260 contributors: mct - updated : 10-05-2017
HGNC name chromosome 14 open reading frame 101
HGNC id 20185
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • C terminus of the protein might confer subcellular localization specificity or indeed a discrete functionality in one of the organellar membranes
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) CRDS
    Susceptibility
  • to overall survival in non-Hodgkin lymphoma (NHL)
  • Variant & Polymorphism SNP
  • rs4901706, located in the 3prime UTR of TMEM260, was shown to be independently related to overall survival in non-Hodgkin lymphoma (NHL) patients
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS