Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TAS2R38 contributors: mct - updated : 10-10-2011
HGNC name taste receptor, type 2, member 38
HGNC id 9584
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • seven transmembrane segments(7TM) receptor
  • an extracellular ligand binding domain
  • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Tas2r138
    homolog to rattus T2R38
    Homologene
    FAMILY G-protein coupled receptor T2R family
    CATEGORY signaling neurotransmitter , receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • directly influencing on phenylthiocarbamide taste sensitivity and involved in bitter perception
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text G-protein coupled receptor protein signaling pathway
    PATHWAY
    metabolism
    signaling signal transduction , sensory transduction/taste
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional        
    good taster
    constitutional        
    non-taster
    Susceptibility
    Variant & Polymorphism other
  • haplotype Pro-Ala-Val associated with phenotype good taster
  • haplotype Arg-Val-Isoleu associated with phenotype non-taster
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS