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FLASH GENE
Symbol SEC62 contributors: npt - updated : 24-04-2003
HGNC name SEC62 homolog (S. cerevisiae)
HGNC id 11846
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to Drosophila Trp1
homolog to yeast S.cerevisiae Sec62
Homologene
FAMILY
  • SEC62 family
    • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION
  • performing post-translational protein translocation into the ER when involved in Sec61-Sec62-Sec63 complex
  • performing the backward transport of ER proteins subject to the ubiquitin-proteasome-dependent degradation pathway when involved in Sec61-Sec62-Sec63 complex
  • involved in protein transport
    • CELLULAR PROCESS protein, post translation, targeting
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism
    signaling
    a component
  • forming a Sec61-Sec62-Sec63 complex
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding to ribosome-free SEC61 complex and SEC63
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS