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FLASH GENE
Symbol POTED contributors: mct/npt - updated : 14-03-2014
HGNC name POTE ankyrin domain family, member D
HGNC id 23822
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N-terminal cysteine rich domain (CRD), palmitoylated on paired cysteine residues in each CRD motif (palmitoylation is responsible of the strong association with plasma membrane)
  • seven ankyrin repeats
  • spectrin-like helices
  • an alpha-helical C terminus
  • HOMOLOGY
    intraspecies paralog to POTEB, POTEG, POTEH, POTEA, POTEF, POTEE, POTEK
    Homologene
    FAMILY
  • POTE gene family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • playing an important role in reproductive processes
  • might be involved in transmitting signals from the cell surface (Bera 2004)
  • may have a role in apoptosis in the human testis, and involved in apoptosis of testicular germ cells
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • may have a role in apoptosis in the human testis
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS