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FLASH GENE
Symbol PHF5A contributors: - updated : 07-03-2005
HGNC name PHD finger protein 5A
HGNC id 18000
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a PHD-finger-like domain that is flanked by highly basic N- and C-termini
HOMOLOGY
Homologene
FAMILY PHD-finger superfamily
CATEGORY DNA associated , transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus,nucleoplasm
basic FUNCTION
  • maybe acting as a chromatin associated protein
  • small nuclear protein that enhances the response of the connexin 43 gene to estrogen
  • playing a role in the cellular response to estrogen affecting both AF-1 and AF-2 activities of the estrogen receptor alpha
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by estrogen in the myometrium
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS