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FLASH GENE
Symbol ZMAT3 contributors: mct/npt - updated : 11-06-2010
HGNC name zinc finger, matrin type 3
HGNC id 29983
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • three zinc finger domain
  • one nuclear localization signal
  • HOMOLOGY
    interspecies ortholog to murine Wig1
    Homologene
    FAMILY
  • zinc finger protein superfamily
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • playing a role in the TP53-dependent growth regulatory pathway
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
  • TP53 (target of TP53)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   amplification    
    in primary squamous cell carcinoma of the lung
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS