basic FUNCTION
| involved in the early development of brain |
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conserved role of members of the ANP32 family during evolution in the modulation of cell signalling and transduction of gene expression to regulate the morphology and dynamics of the cytoskeleton, cell adhesion, neural development or cerebellar morphogenesis |
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mediates potentially synaptogenesis process by modulating activity of PPP2R4 |
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play potentially an important role in brain morphogenesis and synaptic development |
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it appears to play a role in the regulation of fine motor functions |
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ANP32A, ANP32B, ANP32E represent an important node of physiological regulation by virtue of their diverse biochemical activities |
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histone chaperone ANP32E removes H2AFZ from DNA double-strand breaks and promotes nucleosome reorganization and DNA repair |