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FLASH GENE
Symbol TGM7 contributors: mct - updated : 04-06-2019
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • conserved Cys-His-Asp triad
  • one calcium binding domain
  • HOMOLOGY
    Homologene
    FAMILY transglutaminase family
    CATEGORY
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • catalyzing the cross-linking of proteins and the conjugation of polyamines to proteins
  • TGM2 (and possibly also TGM3, TGM7) gained vital functions which have not been fully revealed, yet
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral fusion      
    UBAP1-TGM7, was unique to clear cell (CC) epithelial ovarian cancer (EOC) tumors
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS