Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ZNF397 contributors: mct - updated : 15-02-2011
HGNC name zinc finger protein 397
HGNC id 18818
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a SCAN domain in the N-terminal region, necessary but not sufficient for centromere localisation
  • nine consecutive C(2)H(2) zinc finger repeats in the C-terminal region
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    text co-localisation of ZNF397 with the constitutive centromere protein CENPA during interphase and early prophase
    basic FUNCTION
  • may be involved in transcriptional regulation
  • interphase to early prophase-specific and SCAN domain-containing mammalian centromere protein with a possible role in transcription at the centromere
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS