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FLASH GENE
Symbol ZNF366 contributors: mlc - updated : 07-11-2007
HGNC name zinc finger protein 366
HGNC id 18316
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • eleven zinc finger motifs of the C2H2 type
  • a proline-rich region
  • an acidic region
  • conjugated MetalloP
    HOMOLOGY
    interspecies homolog to murine DC- script (80 p 100)
    Homologene
    FAMILY zinc finger protein family
    CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • ESR1-interacting protein, which is a potent corepressor of ESR1 activity
  • may play an important role in regulating the expression of genes in response to estrogen
  • dendritic cell marker that could be involved in transcriptional repression
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
  • PLAG1
  • interacting with ESR1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS